A biology-guided artificial intelligence model applied to routine pathology slides accurately predicted outcomes and response ...
A computational method called scSurv, developed by researchers at Institute of Science Tokyo, links individual cells to patient outcomes using widely available bulk RNA sequencing data. The approach ...
An open-label, phase I trial of the SIRPα monoclonal antibody, BI 770371, alone and in combination with the PD-1 inhibitor ezabenlimab in patients with advanced solid tumors. This is an ASCO Meeting ...
Physiologically Based Pharmacokinetic Model to Assess the Drug-Drug-Gene Interaction Potential of Belzutifan in Combination With Cyclin-Dependent Kinase 4/6 Inhibitors A total of 14,177 patients were ...
For years, cell and gene therapies were mainly associated with rare and orphan diseases, those that impact small patient groups and lack effective treatment options. However, recent developments in ...
CD19-CAR T-cell treatment is a novel option of deep B cell depletion with promising results across different rheumatologic and musculoskeletal diseases (RMD). This and other cell-depleting approaches ...
The scSurv is a method that deconvolutes bulk RNA-seq data into individual single cells using scRNA-seq data and performs survival analysis with an extended Cox proportional hazards model. This ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results